Neutrophil extracellular traps, local IL-8 expression, and cytotoxic T-lymphocyte absence in the lungs of fatal COVID-19: a retrospective histopathology cohort study
<p><strong>Background:</strong> Excessive inflammation is pathogenic in the pneumonitis associated with severe COVID-19. Neutrophils are among the most abundantly present leukocytes in the inflammatory infiltrates and may form neutrophil extracellular traps (NETs) under the local i...
Main Authors: | Melero, I, Villalba-Esparza, M, Recalde-Zamacona, B, Álvaro, T, Argueta, A, García-Tobar, L, Álvarez-Gigli, L, Sainz, C, Garcia-Ros, D, Toledo, E, Abengozar-Muela, M, Fernandez-Alonso, M, Rodriguez-Moreno, M, Reina, G, Carmona-Torre, F, Quiroga, JA, Pozo, JD, Cross, A, Echeveste, J, Lozano, M, Ho, L-P, Klenerman, P, Issa, F, Landecho, M, Andrea, CD |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2022
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