Distribution of a persistent sodium current across the ventricular wall in guinea pigs.
A tetrodotoxin-sensitive persistent sodium current, I(pNa), was found in guinea pig ventricular myocytes by whole-cell patch clamping. This current was characterized in cells derived from the basal left ventricular subendocardium, midmyocardium, and subepicardium. Midmyocardial cells show a statisti...
Main Authors: | Sakmann, B, Spindler, A, Bryant, S, Linz, K, Noble, D |
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Format: | Journal article |
Language: | English |
Published: |
2000
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