Influenza virus activation of the interferon system.
The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summ...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
2015
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| _version_ | 1797082840705269760 |
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| author | Killip, M Fodor, E Randall, R |
| author_facet | Killip, M Fodor, E Randall, R |
| author_sort | Killip, M |
| collection | OXFORD |
| description | The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summarise recent work regarding activation of the type I IFN response by influenza viruses, including attempts to identify the viral RNA responsible for IFN induction, the stage of the virus life cycle at which it is generated and the role of defective viruses in this process. |
| first_indexed | 2024-03-07T01:33:34Z |
| format | Journal article |
| id | oxford-uuid:9461a96a-821e-4838-a555-5106aaa09d03 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:33:34Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:9461a96a-821e-4838-a555-5106aaa09d032022-03-26T23:39:06ZInfluenza virus activation of the interferon system.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9461a96a-821e-4838-a555-5106aaa09d03EnglishSymplectic Elements at OxfordElsevier2015Killip, MFodor, ERandall, RThe host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to establish an infection. Many advances have been made in recent years in understanding the interactions between influenza viruses and the interferon system. In this review, we summarise recent work regarding activation of the type I IFN response by influenza viruses, including attempts to identify the viral RNA responsible for IFN induction, the stage of the virus life cycle at which it is generated and the role of defective viruses in this process. |
| spellingShingle | Killip, M Fodor, E Randall, R Influenza virus activation of the interferon system. |
| title | Influenza virus activation of the interferon system. |
| title_full | Influenza virus activation of the interferon system. |
| title_fullStr | Influenza virus activation of the interferon system. |
| title_full_unstemmed | Influenza virus activation of the interferon system. |
| title_short | Influenza virus activation of the interferon system. |
| title_sort | influenza virus activation of the interferon system |
| work_keys_str_mv | AT killipm influenzavirusactivationoftheinterferonsystem AT fodore influenzavirusactivationoftheinterferonsystem AT randallr influenzavirusactivationoftheinterferonsystem |