The bromodomain interaction module

-N-acetylation of lysine residues (K ac) is one of the most abundant post-translation modifications (PTMs) in the human proteome. In the nucleus, acetylation of histones has been linked to transcriptional activation of genes but the functional consequences of most acetylation events and proteins rec...

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Autors principals: Filippakopoulos, P, Knapp, S
Format: Journal article
Idioma:English
Publicat: 2012