Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells.

Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells.

We wish to construct a mouse model for the human inherited disease cystic fibrosis. We describe here the successful targeting in embryonal stem cells of the murine homologue (Cftr) of the cystic fibrosis transmembrane conductance regulator gene, as the first critical step towards this end. The targe...

书目详细资料
Main Authors:	Dorin, JR, Dickinson, P, Emslie, E, Clarke, A, Dobbie, L, Hooper, M, Halford, S, Wainwright, B, Porteous, D
格式:	Journal article
语言:	English
出版:	Kluwer Academic Publishers 1992

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