Developing a personalized heterologous prime boost vaccination strategy for tumor therapy
The limited success of therapeutic cancer vaccines to date is likely due to sub-optimal generation of anti-tumor CD8 T cells and insufficient tumor microenvironment (TME) modulation. In this study, a novel intravenous (IV) heterologous prime-boost vaccination strategy with a self-assembling neoantig...
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| Format: | Thesis |
| Language: | English |
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2021
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