Parental mental illness and eating disorders in offspring.

OBJECTIVE: To investigate which parental mental illnesses are associated with eating disorders in their offspring. METHOD: We used data from a record-linkage cohort study of 158,679 children aged 12-24 years at the end of follow-up, resident in Stockholm County from 2001 to 2007, to investigate whet...

Full description

Bibliographic Details
Main Authors: Bould, H, Koupil, I, Dalman, C, DeStavola, B, Lewis, G, Magnusson, C
Format: Journal article
Language:English
Published: Wiley 2015
_version_ 1797082932863565824
author Bould, H
Koupil, I
Dalman, C
DeStavola, B
Lewis, G
Magnusson, C
author_facet Bould, H
Koupil, I
Dalman, C
DeStavola, B
Lewis, G
Magnusson, C
author_sort Bould, H
collection OXFORD
description OBJECTIVE: To investigate which parental mental illnesses are associated with eating disorders in their offspring. METHOD: We used data from a record-linkage cohort study of 158,679 children aged 12-24 years at the end of follow-up, resident in Stockholm County from 2001 to 2007, to investigate whether different parental mental illnesses are risk factors for eating disorders in their offspring. The outcome measure was diagnosis of any eating disorder, either from an ICD or DSM-IV code, or inferred from an appointment at a specialist eating disorder clinic. RESULTS: Mental illness in parents is a risk factor for eating disorders in female offspring (Adjusted Hazard Ratio (AHR) 1.57 (95% CI 1.42, 1.92), p < 0.0001). Risk of eating disorders is increased if there is a parental diagnosis of bipolar affective disorder (AHR 2.28 (95% CI 1.39, 3.72), p = 0.004), personality disorder (AHR 1.57 (95% CI 1.01, 2.44), p = 0.043) or anxiety/depression (AHR 1.57 (95% CI 1.32, 1.86), p < 0.0001). There is a lack of statistical evidence for an association with parental schizophrenia (AHR 1.41 (95% CI 0.96, 2.07), p = 0.08), and somatoform disorder (AHR 1.25 (95% CI 0.74, 2.13), p = 0.40). There is no support for a relationship between parental substance misuse and eating disorders in children (AHR 1.08 (95% CI 0.82, 1.43), p = 0.57). DISCUSSION: Parental mental illness, specifically parental anxiety, depression, bipolar affective disorder, and personality disorders, are risk factors for eating disorders in their offspring. © 2014 Wiley Periodicals, Inc. Int J Eat Disord 2014; (Int J Eat Disord 2014).
first_indexed 2024-03-07T01:34:56Z
format Journal article
id oxford-uuid:94d7a879-9526-435c-baa8-602528fcceed
institution University of Oxford
language English
last_indexed 2024-03-07T01:34:56Z
publishDate 2015
publisher Wiley
record_format dspace
spelling oxford-uuid:94d7a879-9526-435c-baa8-602528fcceed2022-03-26T23:42:06ZParental mental illness and eating disorders in offspring.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:94d7a879-9526-435c-baa8-602528fcceedEnglishSymplectic Elements at OxfordWiley2015Bould, HKoupil, IDalman, CDeStavola, BLewis, GMagnusson, COBJECTIVE: To investigate which parental mental illnesses are associated with eating disorders in their offspring. METHOD: We used data from a record-linkage cohort study of 158,679 children aged 12-24 years at the end of follow-up, resident in Stockholm County from 2001 to 2007, to investigate whether different parental mental illnesses are risk factors for eating disorders in their offspring. The outcome measure was diagnosis of any eating disorder, either from an ICD or DSM-IV code, or inferred from an appointment at a specialist eating disorder clinic. RESULTS: Mental illness in parents is a risk factor for eating disorders in female offspring (Adjusted Hazard Ratio (AHR) 1.57 (95% CI 1.42, 1.92), p < 0.0001). Risk of eating disorders is increased if there is a parental diagnosis of bipolar affective disorder (AHR 2.28 (95% CI 1.39, 3.72), p = 0.004), personality disorder (AHR 1.57 (95% CI 1.01, 2.44), p = 0.043) or anxiety/depression (AHR 1.57 (95% CI 1.32, 1.86), p < 0.0001). There is a lack of statistical evidence for an association with parental schizophrenia (AHR 1.41 (95% CI 0.96, 2.07), p = 0.08), and somatoform disorder (AHR 1.25 (95% CI 0.74, 2.13), p = 0.40). There is no support for a relationship between parental substance misuse and eating disorders in children (AHR 1.08 (95% CI 0.82, 1.43), p = 0.57). DISCUSSION: Parental mental illness, specifically parental anxiety, depression, bipolar affective disorder, and personality disorders, are risk factors for eating disorders in their offspring. © 2014 Wiley Periodicals, Inc. Int J Eat Disord 2014; (Int J Eat Disord 2014).
spellingShingle Bould, H
Koupil, I
Dalman, C
DeStavola, B
Lewis, G
Magnusson, C
Parental mental illness and eating disorders in offspring.
title Parental mental illness and eating disorders in offspring.
title_full Parental mental illness and eating disorders in offspring.
title_fullStr Parental mental illness and eating disorders in offspring.
title_full_unstemmed Parental mental illness and eating disorders in offspring.
title_short Parental mental illness and eating disorders in offspring.
title_sort parental mental illness and eating disorders in offspring
work_keys_str_mv AT bouldh parentalmentalillnessandeatingdisordersinoffspring
AT koupili parentalmentalillnessandeatingdisordersinoffspring
AT dalmanc parentalmentalillnessandeatingdisordersinoffspring
AT destavolab parentalmentalillnessandeatingdisordersinoffspring
AT lewisg parentalmentalillnessandeatingdisordersinoffspring
AT magnussonc parentalmentalillnessandeatingdisordersinoffspring