Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.

Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.

A significant portion of the genome is transcribed as long noncoding RNAs (lncRNAs), several of which are known to control gene expression. The repertoire and regulation of lncRNAs in disease-relevant tissues, however, has not been systematically explored. We report a comprehensive strand-specific t...

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Bibliographic Details
Main Authors: Morán, I, Akerman, I, van de Bunt, M, Xie, R, Benazra, M, Nammo, T, Arnes, L, Nakić, N, García-Hurtado, J, Rodríguez-Seguí, S, Pasquali, L, Sauty-Colace, C, Beucher, A, Scharfmann, R, van Arensbergen, J, Johnson, P, Berry, A, Lee, C, Harkins, T, Gmyr, V, Pattou, F, Kerr-Conte, J, Piemonti, L, Berney, T, Hanley, N
Format: Journal article
Language:English
Published: 2012

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