BLOCKING THE INHIBITORY CD94/NKG2A NK CELL RECEPTOR WITH A NOVEL ANTI-NKG2A MAB ENHANCES THE SUSCEPTIBILITY OF RHEUMATOID ARTHRITIS FIBROBLAST-LIKE SYNOVIOCYTES (FLS) TO NK CELL-MEDIATED CYTOTOXICITY

Antzeko izenburuak

• HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.
  nork: King, A, et al.
  Argitaratua: (2000)
• The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells
  nork: Meike Kaulfuss, et al.
  Argitaratua: (2023-06-01)
• Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
  nork: Nielsen, N, et al.
  Argitaratua: (2014)
• CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors
  nork: Chiara Giordano, et al.
  Argitaratua: (2025-01-01)
• Inhibitory NKG2A+ and absent activating NKG2C+ NK cell responses are associated with the development of EBV+ lymphomas
  nork: Hannes Vietzen, et al.
  Argitaratua: (2023-06-01)