A scaffold for X chromosome inactivation.

X chromosome inactivation (XCI), the silencing of one of the two X chromosomes in XX female cells, equalises the dosage of X-linked genes relative to XY males. The process is mediated by the non-coding RNA X inactive specific transcript (Xist) that binds in cis and propagates along the inactive X ch...

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Hlavní autoři: Tattermusch, A, Brockdorff, N
Médium: Journal article
Jazyk:English
Vydáno: 2011