A statistical method for predicting classical HLA alleles from SNP data.

Genetic variation at classical HLA alleles is a crucial determinant of transplant success and susceptibility to a large number of infectious and autoimmune diseases. However, large-scale studies involving classical type I and type II HLA alleles might be limited by the cost of allele-typing technolo...

Description complète

Détails bibliographiques
Auteurs principaux: Leslie, S, Donnelly, P, McVean, G
Format: Journal article
Langue:English
Publié: 2008