A "tag-and-modify" approach to site-selective protein modification.

Covalent modification can expand a protein's functional capacity. Fluorescent or radioactive labeling, for instance, allows imaging of a protein in real time. Labeling with an affinity probe enables isolation of target proteins and other interacting molecules. At the other end of this functiona...

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Bibliographic Details
Main Authors: Chalker, J, Bernardes, G, Davis, B
Format: Journal article
Language:English
Published: 2011