Development of a polygenic risk score to improve screening for fracture risk: a genetic risk prediction study.

Development of a polygenic risk score to improve screening for fracture risk: a genetic risk prediction study.

BACKGROUND:<br>Since screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low genetic risk. We therefore tested whether a p...

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Main Authors: Forgetta, V, Forest, M, Durand, A, Bhatnagar, S, Kemp, JP, Nethander, M, Evans, D, Morris, JA, Kiel, DP, Rivadeneira, F, Johansson, H, Harvey, NC, Mellström, D, Karlsson, M, Cooper, C, Evans, DM, Keller-Baruch, J, Clarke, R, Kanis, JA, Orwoll, E, McCloskey, EV, Ohlsson, C, Pineau, J, Leslie, WD, Greenwood, CMT, Richards, JB
Format: Journal article
Language:English
Published: Public Library of Science 2020

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