Protective cellular immunity generated by cross-presenting recombinant overlapping peptide proteins

Priming of naive CD8+ and CD4+ T cells by dendritic cells (DCs) requires effective antigen presentation on both MHC class I and II molecules. We have developed a novel technology to use recombinant overlapping peptides (ROP) that stimulate both CD8+ and CD4+ T cell immune responses. The single chain...

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Bibliographic Details
Main Authors: Cai, L, Zhang, J, Zhu, R, Shi, W, Xia, X, Edwards, M, Finch, W, Coombs, A, Gao, J, Chen, K, Owen, S, Jiang, S, Lu, W
Format: Journal article
Language:English
Published: Impact Journals 2017