Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database
<strong>Objectives<br></strong> We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves. <br><strong>Methods<br></strong> Using a large-scale hospital-based database,...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Cell Press
2023
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| _version_ | 1811139181503578112 |
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| author | Suzuki, T Taniguchi, Y Komiyama, J Kuno, T Adomi, M Abe, T Inokuchi, R Miyawaki, A Imai, S Saito, M Ohbe, H Aso, S Kamio, T Tamiya, N Iwagami, M |
| author_facet | Suzuki, T Taniguchi, Y Komiyama, J Kuno, T Adomi, M Abe, T Inokuchi, R Miyawaki, A Imai, S Saito, M Ohbe, H Aso, S Kamio, T Tamiya, N Iwagami, M |
| author_sort | Suzuki, T |
| collection | OXFORD |
| description | <strong>Objectives<br></strong>
We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves.
<br><strong>Methods<br></strong>
Using a large-scale hospital-based database, we identified patients hospitalized for COVID-19 in the first (January–June 2020), second (June–October 2020), third (October 2020–February 2021), fourth (March–June 2021), and fifth (June–December 2021) waves. We summarized patient characteristics, healthcare utilization, and in-hospital mortality during each wave and performed multivariable logistic regression analyses for in-hospital mortality.
<br><strong>Results<br></strong>
From the first to fifth waves, the number of patients (mean age ± standard deviation, years) was 2958 (61.2 ± 22.8), 7981 (55.6 ± 25.3), 18,788 (63.6 ± 22.9), 17,729 (60.6 ± 22.6), and 23,656 (51.2 ± 22.3), respectively. There were 190 (6.4%), 363 (4.5%), 1261 (6.7%), 1081 (6.1%), and 762 (3.2%) in-hospital deaths, respectively. The adjusted odds ratios for in-hospital deaths (95% confidence interval) were 0.78 (0.65–0.95), 0.94 (0.79–1.12), 0.99 (0.84–1.18), 0.77 (0.65–0.92), in the second to fifth waves, respectively, compared with the first wave.
<br><strong>Conclusions<br></strong>
In-hospital COVID-19 mortality improved from the first to the second wave; however, during the third and fourth waves, mortality was as serious as in the first wave. Although in-hospital mortality during the fifth wave improved, careful monitoring is needed for upcoming waves, considering changing patient and viral characteristics. |
| first_indexed | 2024-09-25T04:02:00Z |
| format | Journal article |
| id | oxford-uuid:958a6140-fe72-4ba0-866d-422c5924cce6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:02:00Z |
| publishDate | 2023 |
| publisher | Cell Press |
| record_format | dspace |
| spelling | oxford-uuid:958a6140-fe72-4ba0-866d-422c5924cce62024-04-29T15:02:28ZCharacteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision databaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:958a6140-fe72-4ba0-866d-422c5924cce6EnglishSymplectic ElementsCell Press2023Suzuki, TTaniguchi, YKomiyama, JKuno, TAdomi, MAbe, TInokuchi, RMiyawaki, AImai, SSaito, MOhbe, HAso, SKamio, TTamiya, NIwagami, M<strong>Objectives<br></strong> We aimed to describe patient characteristics, healthcare utilization, and in-hospital mortality among patients with COVID-19 in Japan across waves. <br><strong>Methods<br></strong> Using a large-scale hospital-based database, we identified patients hospitalized for COVID-19 in the first (January–June 2020), second (June–October 2020), third (October 2020–February 2021), fourth (March–June 2021), and fifth (June–December 2021) waves. We summarized patient characteristics, healthcare utilization, and in-hospital mortality during each wave and performed multivariable logistic regression analyses for in-hospital mortality. <br><strong>Results<br></strong> From the first to fifth waves, the number of patients (mean age ± standard deviation, years) was 2958 (61.2 ± 22.8), 7981 (55.6 ± 25.3), 18,788 (63.6 ± 22.9), 17,729 (60.6 ± 22.6), and 23,656 (51.2 ± 22.3), respectively. There were 190 (6.4%), 363 (4.5%), 1261 (6.7%), 1081 (6.1%), and 762 (3.2%) in-hospital deaths, respectively. The adjusted odds ratios for in-hospital deaths (95% confidence interval) were 0.78 (0.65–0.95), 0.94 (0.79–1.12), 0.99 (0.84–1.18), 0.77 (0.65–0.92), in the second to fifth waves, respectively, compared with the first wave. <br><strong>Conclusions<br></strong> In-hospital COVID-19 mortality improved from the first to the second wave; however, during the third and fourth waves, mortality was as serious as in the first wave. Although in-hospital mortality during the fifth wave improved, careful monitoring is needed for upcoming waves, considering changing patient and viral characteristics. |
| spellingShingle | Suzuki, T Taniguchi, Y Komiyama, J Kuno, T Adomi, M Abe, T Inokuchi, R Miyawaki, A Imai, S Saito, M Ohbe, H Aso, S Kamio, T Tamiya, N Iwagami, M Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title | Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title_full | Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title_fullStr | Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title_full_unstemmed | Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title_short | Characteristics and in-hospital mortality of patients with COVID-19 from the first to fifth waves of the pandemic in 2020 and 2021 in the Japanese Medical Data Vision database |
| title_sort | characteristics and in hospital mortality of patients with covid 19 from the first to fifth waves of the pandemic in 2020 and 2021 in the japanese medical data vision database |
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