Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells.

The type 4 phosphodiesterase (PDE) family comprises four enzymes (4A, 4B, 4C and 4D) that are characterized by their specificity for cAMP and selective inhibition by the anti-depressant drug rolipram (4-[3-(cyclopentoxyl)-4-methoxyphenyl]2-pyrrolidone). In common with other PDEs, they consist of a c...

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Những tác giả chính: Owens, R, Catterall, C, Batty, D, Jappy, J, Russell, A, Smith, B, O'Connell, J, Perry, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1997