A new high-throughput method utilizing porous silica-based nano-composites for the determination of partition coefficients of drug candidates.
We show that highly porous silica-based nanoparticles prepared via micro-emulsion and sol-gel techniques are stable colloids in aqueous solution. By incorporating a magnetic core into the porous silica nano-composite, it is found that the material can be rapidly separated (precipitated) upon exposur...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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