Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining.

We developed a biochemical kinetics approach to describe the repair of double-strand breaks (DSBs) produced by low-LET radiation by modeling molecular events associated with non-homologous end joining (NHEJ). A system of coupled nonlinear ordinary differential equations describes the induction of DS...

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Bibliographic Details
Main Authors: Cucinotta, F, Pluth, J, Anderson, J, Harper, J, O'Neill, P
Format: Journal article
Language:English
Published: 2008

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