Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators

Oncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators

Enadenotucirev (EnAd) is a chimeric group B adenovirus isolated by bioselection from a library of adenovirus serotypes. It replicates selectively in and kills a diverse range of carcinoma cells, shows effective anticancer activity in preclinical systems, and is currently undergoing phase I/II clinic...

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Bibliographic Details
Main Authors: Dyer, A, Di, Y, Calderon, H, Illingworth, S, Kueberuwa, G, Tedcastle, A, Jakeman, P, Chia, S, Brown, A, Silva, M, Barlow, D, Beadle, J, Hermiston, T, Ferguson, D, Champion, B, Fisher, K, Seymour, L
Format: Journal article
Language:English
Published: Elsevier 2016

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