Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60.
NKG2D is a potent activating receptor on natural killer cells, T cells, and macrophages. Mouse NKG2D interacts with two cell surface ligands related to class I MHC molecules: RAE1 and H60. We used soluble versions of NKG2D, RAE1, and H60 to characterize their interactions. RAE1 and H60 each bind NKG...
Príomhchruthaitheoirí: | O'Callaghan, C, Cerwenka, A, Willcox, B, Lanier, L, Bjorkman, P |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2001
|
Míreanna comhchosúla
Míreanna comhchosúla
-
Cutting edge: the minor histocompatibility antigen H60 peptide interacts with both H-2Kb and NKG2D.
de réir: Cerwenka, A, et al.
Foilsithe / Cruthaithe: (2002) -
NKG2D
de réir: O'Callaghan, C
Foilsithe / Cruthaithe: (2009) -
Regulation of ligands for the activating receptor NKG2D.
de réir: Mistry, A, et al.
Foilsithe / Cruthaithe: (2007) -
Structural and energetic aspects of multispecific immune recognition by NKG2D.
de réir: O'Callaghan, C, et al.
Foilsithe / Cruthaithe: (2003) -
Cellular metabolism controls NKG2D-dependent cellular immunogenicity
de réir: McCarthy, M, et al.
Foilsithe / Cruthaithe: (2013)