Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2

Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2

The Omicron strains of SARS-CoV-2 pose a significant challenge to the development of effective antibody-based treatments as immune evasion has compromised most available immune therapeutics. Therefore, in the ‘arms race’ with the virus, there is a continuing need to identify new biologics for the pr...

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Bibliographic Details
Main Authors: Cornish, K, Huo, J, Jones, L, Sharma, P, Thrush, JW, Abdelkarim, S, Kipar, A, Ramadurai, S, Weckener, M, Mikolajek, H, Liu, S, Buckle, I, Bentley, E, Kirby, A, Han, X, Laidlaw, SM, Hill, M, Eyssen, L, Norman, C, Le Bas, A, Clarke, J, James, W, Stewart, JP, Carroll, M, Naismith, JH, Owens, RJ
Format: Journal article
Language:English
Published: The Royal Society 2024

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