An integrative computational model for intestinal tissue renewal

Objectives: The luminal surface of the gut is lined with a monolayer of epithelial cells that acts as a nutrient absorptive engine and protective barrier. To maintain its integrity and functionality, the epithelium is renewed every few days. Theoretical models are powerful tools that can be used to...

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Bibliographic Details
Main Authors: van Leeuwen, I, Mirams, G, Walter, A, Fletcher, A, Murray, P, Osbourne, J, Varma, S, Young, S, Cooper, J, Doyle, B, Pitt-Francis, J, Momtahan, L, Pathmanathan, P, Whiteley, J, Chapman, S, Gavaghan, D, Jensen, O, King, J, Maini, P, Waters, S, Byrne, H
Format: Journal article
Published: Wiley Blackwell 2009