Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes.
T cells survey antigen-presenting dendritic cells (DCs) by migrating through DC networks, arresting and maintaining contact with DCs for several hours after encountering high-potency complexes of peptide and major histocompatibility complex (pMHC), leading to T cell activation. The effects of low-po...
Main Authors: | Skokos, D, Shakhar, G, Varma, R, Waite, J, Cameron, T, Lindquist, R, Schwickert, T, Nussenzweig, M, Dustin, M |
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Format: | Journal article |
Language: | English |
Published: |
2007
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