Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts
Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the differe...
Main Authors: | , , , , , , |
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Format: | Journal article |
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2010
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author | Murray, P Kang, J Mirams, G Shin, S Byrne, H Maini, P Cho, K |
author_facet | Murray, P Kang, J Mirams, G Shin, S Byrne, H Maini, P Cho, K |
author_sort | Murray, P |
collection | OXFORD |
description | Experimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the different regions of the small and large intestines. In this article, we construct a partial differential equation model of a single colonic crypt that |
first_indexed | 2024-03-07T01:39:06Z |
format | Journal article |
id | oxford-uuid:9637e0c4-7c6d-49b4-a919-ef7be18986a7 |
institution | University of Oxford |
last_indexed | 2024-03-07T01:39:06Z |
publishDate | 2010 |
record_format | dspace |
spelling | oxford-uuid:9637e0c4-7c6d-49b4-a919-ef7be18986a72022-03-26T23:51:34ZModelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal CryptsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9637e0c4-7c6d-49b4-a919-ef7be18986a7Department of Computer Science2010Murray, PKang, JMirams, GShin, SByrne, HMaini, PCho, KExperimental data (e.g., genetic lineage and cell population studies) on intestinal crypts reveal that regulatory features of crypt behavior, such as control via morphogen gradients, are remarkably well conserved among numerous organisms (e.g., from mouse and rat to human) and throughout the different regions of the small and large intestines. In this article, we construct a partial differential equation model of a single colonic crypt that |
spellingShingle | Murray, P Kang, J Mirams, G Shin, S Byrne, H Maini, P Cho, K Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title | Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title_full | Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title_fullStr | Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title_full_unstemmed | Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title_short | Modelling Spatially Regulated beta−Catenin Dynamics and Invasion in Intestinal Crypts |
title_sort | modelling spatially regulated beta catenin dynamics and invasion in intestinal crypts |
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