Advances in understanding chromosome silencing by the long non-coding RNA Xist.
In female mammals, one of the two X chromosomes becomes genetically silenced to compensate for dosage imbalance of X-linked genes between XX females and XY males. X chromosome inactivation (X-inactivation) is a classical model for epigenetic gene regulation in mammals and has been studied for half a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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