BIFUNCTIONAL CHIRAL AUXILIARIES-3 - SYNTHESIS OF HOMOCHIRAL 1,3-DIOLS VIA ASYMMETRIC ALDOL REACTIONS OF DIALKYLBORON ENOLATES OF 1,3-DIPROPIONYL-TRANS-4,5-DIPHENYL-IMIDAZOLIDIN-2-ONE AND ALDEHYDES
Dibutylboron enolates derived from both racemic and homochiral 1,3-dipropionyl-trans-4,5-diphenylimidazolidin-2-one 3 react with aldehydes in highly diastereoselective dialdol reactions to give, after reductive cleavage of the acyl sidechain, substituted 1,3-diols. © 1991.
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1991
|