Improving the affinity and activity of CYP101D2 for hydrophobic substrates.
CYP101D2 is a cytochrome P450 monooxygenase from Novosphingobium aromaticivorans which is closely related to CYP101A1 (P450cam) from Pseudomonas putida. Both enzymes selectively hydroxylate camphor to 5-exo-hydroxycamphor, and the residues that line the active sites of both enzymes are similar inclu...
Main Authors: | , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2013
|