Targeting the type 1 insulin-like growth factor receptor as anti-cancer treatment.
The type 1 insulin-like growth factor receptor (IGF1R) is overexpressed by many tumors, and mediates growth, motility and protection from apoptosis. Inhibition of IGF1R expression or function has been shown to block tumor growth and metastasis, and enhance sensitivity to cytotoxic drugs and irradiat...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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