Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.

We mapped a high-penetrance gene (CRAC1; also known as HMPS) associated with colorectal cancer (CRC) in the Ashkenazi population to a 0.6-Mb region on chromosome 15 containing SCG5 (also known as SGNE1), GREM1 and FMN1. We hypothesized that the CRAC1 locus harbored low-penetrance variants that incre...

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Detalles Bibliográficos
Autores principales:	Jaeger, E, Webb, E, Howarth, K, Carvajal-Carmona, L, Rowan, A, Broderick, P, Walther, A, Spain, S, Pittman, A, Kemp, Z, Sullivan, K, Heinimann, K, Lubbe, S, Domingo, E, Barclay, E, Martin, L, Gorman, M, Chandler, I, Vijayakrishnan, J, Wood, W, Papaemmanuil, E, Penegar, S, Qureshi, M, Farrington, S, Tenesa, A
Formato:	Journal article
Lenguaje:	English
Publicado:	2008

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.

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