The early cellular events that control mechano-inflammatory signalling after cartilage injury

The early cellular events that control mechano-inflammatory signalling after cartilage injury

Osteoarthritis (OA) is a degenerative joint disease that has no disease- modifying drug licenced for its treatment. Mechanical injury of cartilage is a principal risk factor in osteoarthritis (OA). Recent insights arising from our group demonstrate that mechano-sensitive intracellular signalling dri...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Chan, C, Vincent, T
Formaat:	Thesis
Taal:	English
Gepubliceerd in:	2023
Onderwerpen:	Osteoarthritis Osteoarthritis > Animal models

Gelijkaardige items

Exploring mechano-structural processes in osteoarthritis
door: Chen, Y
Gepubliceerd in: (2017)

Understanding cartilage protection in OA and injury: a spectrum of possibilities
door: Anand O. Masson, et al.
Gepubliceerd in: (2020-07-01)

Network-based modelling of mechano-inflammatory chondrocyte regulation in early osteoarthritis
door: Maria Segarra-Queralt, et al.
Gepubliceerd in: (2023-02-01)

Promising results of captopril in improving knee arthrofibrosis and cartilage status: an animal model study
door: Seyed Ali Hashemi, et al.
Gepubliceerd in: (2022-01-01)

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants
door: Evelyn Houtman, et al.
Gepubliceerd in: (2021-08-01)

Developing an experimental model of early knee osteoarthritis after medial meniscus posterior root release: an in vivo study
door: Lika Dzidzishvili, et al.
Gepubliceerd in: (2022-01-01)

AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis
door: Dan Yi, et al.
Gepubliceerd in: (2021-06-01)

The role of retinoic acid in cartilage mechanoflammation
door: Kamalathevan, P
Gepubliceerd in: (2022)

STUDY ON THE ROLE AND MECHANISM OF MICRORNA-650/WNT1 IN THE REPAIR OF ARTICULAR CARTILAGE INJURY
door: Hui Liu, et al.
Gepubliceerd in: (2024-10-01)

Cartilage regeneration effect of orally administered Zingiber officinale against MIA-induced osteoarthritis in rats
door: Ganabadi, Shanti, et al.
Gepubliceerd in: (2010)

Determination of the Prevalence of Knee and Hip Clinical Osteoarthritis in the Active Professional Male Footballer and Its Association with Pain, Function, Injury and Surgery
door: Lervasen Pillay, et al.
Gepubliceerd in: (2023-07-01)

Commentary: Scoring Flaw in the Persian Version of Knee Injury and Osteoarthritis Outcome Score: A comment on “Validation of a Persian-version of Knee injury and Osteoarthritis Outcome Score (KOOS) in Iranians with knee injuries. Osteoarthritis Cartilage 2008 Oct;16(10):1178-82”
door: Zahra Sadat Rezaeian
Gepubliceerd in: (2021-04-01)

Effects of alendronate on cartilage lesions and micro-architecture deterioration of subchondral bone in patellofemoral osteoarthritic ovariectomized rats with patella-baja
door: Mingjian Bei, et al.
Gepubliceerd in: (2024-03-01)

Targeting Cartilage Degradation in Osteoarthritis
door: Oliver McClurg, et al.
Gepubliceerd in: (2021-02-01)

Early Knee Osteoarthritis Classification and Clinical Evolution: A Longitudinal Observational Pilot Study
door: Luz Herrero-Manley, et al.
Gepubliceerd in: (2023-06-01)

Tribology of enzymatically degraded cartilage mimicking early osteoarthritis
door: Ke Ren, et al.
Gepubliceerd in: (2023-05-01)

Parathyroid hormone (1-34) ameliorates cartilage degeneration and subchondral bone deterioration in collagenase-induced osteoarthritis model in mice
door: Li-tao Shao, et al.
Gepubliceerd in: (2020-10-01)

Animal models of osteoarthritis <subtitle>the benefits and costs of reducing variability</subtitle>
door: Christopher B. Little, et al.
Gepubliceerd in: (2022-08-01)

Role of global femoral cartilage in assessing severity of primary knee osteoarthritis
door: Naylan Fayez Wahba Khalil, et al.
Gepubliceerd in: (2022-03-01)

The Gasotransmitter Hydrogen Sulfide (H<sub>2</sub>S) Prevents Pathologic Calcification (PC) in Cartilage
door: Sonia Nasi, et al.
Gepubliceerd in: (2021-09-01)

Early osteoarthritis: development of diagnostic criteria
door: L. I. Alekseeva, et al.
Gepubliceerd in: (2020-09-01)

Serum lipid biomarkers and inflammatory cytokines associated with onset and clinical status of patients with early knee osteoarthritis
door: Luz Herrero-Manley, et al.
Gepubliceerd in: (2023-03-01)

Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover
door: Jonathan J. Bjerre-Bastos, et al.
Gepubliceerd in: (2020-06-01)

Metabolomic Profiles and Pathways in Osteoarthritic Human Cartilage: A Comparative Analysis with Healthy Cartilage
door: Hope D. Welhaven, et al.
Gepubliceerd in: (2024-03-01)

Gentiopicroside ameliorates the lipopolysaccharide-induced inflammatory response and hypertrophy in chondrocytes
door: Longfei Li, et al.
Gepubliceerd in: (2024-03-01)

Current advances in animal model of meniscal injury: From meniscal injury to osteoarthritis
door: Xiaoyao Peng, et al.
Gepubliceerd in: (2025-01-01)

In vitro inflammatory multi-cellular model of osteoarthritis
door: Ileana Marrero - Berrios, et al.
Gepubliceerd in: (2024-03-01)

Cartilage regeneration in zebrafish depends on Nrg1/ErbB signaling pathway
door: Dora Sapède, et al.
Gepubliceerd in: (2023-04-01)

In vitro evaluation of chondrocytes isolated from osteoarthritic articular cartilage supplemented with edible bird's nest extract /
door: Kamini Nagandran, 1980-, et al.
Gepubliceerd in: (2011)

Articular cartilage morphology and synovial fluid protein biomarkers in the monosodium iodoacetate-induced osteoarthritis rabbit model
door: Tan, Wei Miao @ Rachel
Gepubliceerd in: (2017)

Study protocol for the PICASSO trial: A randomized placebo-controlled trial to investigate the efficacy and safety of intraarticular steroid injections and an occupational therapy intervention in painful inflammatory carpometacarpal-1 osteoarthritis
door: Marthe Gløersen, et al.
Gepubliceerd in: (2025-03-01)

Screening Clinical Changes for the Diagnosis of Early Knee Osteoarthritis: A Cross-Sectional Observational Study
door: Ana Alabajos-Cea, et al.
Gepubliceerd in: (2022-10-01)

The Pharmacology of Pain Associated With the Monoiodoacetate Model of Osteoarthritis
door: João de Sousa Valente
Gepubliceerd in: (2019-09-01)

CC-Chemokine Receptor-2 Expression in Osteoblasts Contributes to Cartilage and Bone Damage during Post-Traumatic Osteoarthritis
door: Helen Willcockson, et al.
Gepubliceerd in: (2023-05-01)

Mechanisms of cartilage damage in gout and hyperuricemia
door: E. V. Panina
Gepubliceerd in: (2024-04-01)

Expression of VEGF-A Signaling Pathway in Cartilage of ACLT-induced Osteoarthritis Mouse Model
door: Jia-jia Qian, et al.
Gepubliceerd in: (2021-06-01)

Responding to ACL Injury and its Treatments: Comparative Gene Expression between Articular Cartilage and Synovium
door: Jonah I. Donnenfield, et al.
Gepubliceerd in: (2023-04-01)

In vitro evaluation of chondrocytes isolated from osteoarthritic articular cartilage supplemented with edible bird's nest extract [electronic resource] /
door: Kamini Nagandran, 1980-
Gepubliceerd in: (2011)

Immunomodulatory biomimetic nanoparticles target articular cartilage trauma after systemic administration
door: Chiara Mancino, et al.
Gepubliceerd in: (2023-06-01)

PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis
door: Zili Liu, et al.
Gepubliceerd in: (2021-07-01)