Single-molecule imaging of DNA gyrase activity in living Escherichia coli
Bacterial DNA gyrase introduces negative supercoils into chromosomal DNA and relaxes positive supercoils introduced by replication and transiently by transcription. Removal of these positive supercoils is essential for replication fork progression and for the overall unlinking of the two duplex DNA...
Main Authors: | Stracy, M, Wollman, A, Kaja, E, Gapinski, J, Lee, J, Leek, V, McKie, S, Mitchenall, L, Maxwell, A, Sherratt, D, Leake, M, Zawadzki, P |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2018
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