Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly

Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the microtubule-nucleating pericentriolar material. Centriole duplication is tightly controlled in vivo and aberrations in this process are associated with s...

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Hlavní autoři: Liu, Y, Gupta, G, Barnabas, D, Agircan, F, Mehmood, S, Wu, D, Coyaud, E, Johnson, C, McLaughlin, S, Andreeva, A, Freund, S, Robinson, C, Cheung, S, Raught, B, Pelletier, L, van Breugel, M
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2018