Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformations.
The study of membrane proteins remains a challenging task, and approaches to unravel their dynamics are scarce. Here, we applied hydrogen/deuterium exchange (HDX) coupled to mass spectrometry to probe the motions of a bacterial multidrug ATP-binding cassette (ABC) transporter, BmrA, in the inward-fa...
Main Authors: | Mehmood, S, Domene, M, Forest, E, Jault, J |
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Format: | Journal article |
Language: | English |
Published: |
2012
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