HLA-B57-restricted cytotoxic T-lymphocyte activity in a single infected subject toward two optimal epitopes, one of which is entirely contained within the other.
Viral peptides are recognized by cytotoxic T lymphocytes (CTL) as a complex with major histocompatibility complex (MHC) class I molecules, but the extent to which a single HLA allele can accommodate epitope peptides of different length and sequence is not well characterized. Here we report the ident...
Main Authors: | Goulder, P, Tang, Y, Pelton, S, Walker, B |
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Format: | Journal article |
Language: | English |
Published: |
2000
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