No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine
Hao (2011) reported that the PB2 genes of three swine influenza A viruses were likely generated through homologous recombination between two closely related parental strains. However, we show that Hao's observation is an artifact of incorrect taxon sampling arising through the lack of an approp...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2012
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| _version_ | 1826286365865672704 |
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| author | Boni, M Smith, G Holmes, E Vijaykrishna, D |
| author_facet | Boni, M Smith, G Holmes, E Vijaykrishna, D |
| author_sort | Boni, M |
| collection | OXFORD |
| description | Hao (2011) reported that the PB2 genes of three swine influenza A viruses were likely generated through homologous recombination between two closely related parental strains. However, we show that Hao's observation is an artifact of incorrect taxon sampling arising through the lack of an appropriate evolutionary context. Through rigorous phylogenetic analyses we explain the evolutionary origins of these stains and confirm the lack of any statistical support for intra-segmental recombination. © 2011 Elsevier B.V. |
| first_indexed | 2024-03-07T01:42:40Z |
| format | Journal article |
| id | oxford-uuid:9765af93-768c-4836-9cb9-7b0f2a4699bb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:42:40Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:9765af93-768c-4836-9cb9-7b0f2a4699bb2022-03-26T23:59:15ZNo evidence for intra-segment recombination of 2009 H1N1 influenza virus in swineJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9765af93-768c-4836-9cb9-7b0f2a4699bbEnglishSymplectic Elements at Oxford2012Boni, MSmith, GHolmes, EVijaykrishna, DHao (2011) reported that the PB2 genes of three swine influenza A viruses were likely generated through homologous recombination between two closely related parental strains. However, we show that Hao's observation is an artifact of incorrect taxon sampling arising through the lack of an appropriate evolutionary context. Through rigorous phylogenetic analyses we explain the evolutionary origins of these stains and confirm the lack of any statistical support for intra-segmental recombination. © 2011 Elsevier B.V. |
| spellingShingle | Boni, M Smith, G Holmes, E Vijaykrishna, D No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title | No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title_full | No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title_fullStr | No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title_full_unstemmed | No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title_short | No evidence for intra-segment recombination of 2009 H1N1 influenza virus in swine |
| title_sort | no evidence for intra segment recombination of 2009 h1n1 influenza virus in swine |
| work_keys_str_mv | AT bonim noevidenceforintrasegmentrecombinationof2009h1n1influenzavirusinswine AT smithg noevidenceforintrasegmentrecombinationof2009h1n1influenzavirusinswine AT holmese noevidenceforintrasegmentrecombinationof2009h1n1influenzavirusinswine AT vijaykrishnad noevidenceforintrasegmentrecombinationof2009h1n1influenzavirusinswine |