Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.
We have genotyped 14,436 nonsynonymous SNPs (nsSNPs) and 897 major histocompatibility complex (MHC) tag SNPs from 1,000 independent cases of ankylosing spondylitis (AS), autoimmune thyroid disease (AITD), multiple sclerosis (MS) and breast cancer (BC). Comparing these data against a common control d...
Main Authors: | Burton, P, Clayton, D, Cardon, L, Craddock, N, Deloukas, P, Duncanson, A, Kwiatkowski, D, McCarthy, M, Ouwehand, W, Samani, N, Todd, J, Donnelly, P, Barrett, J, Davison, D, Easton, D, Evans, D, Leung, H, Marchini, J, Morris, A, Spencer, C, Tobin, MD, Attwood, A, Boorman, J, Cant, B, Everson, U |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|
Similar Items
-
Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis.
by: Sellick, G, et al.
Published: (2008) -
HAPGEN2: simulation of multiple disease SNPs.
by: Su, Z, et al.
Published: (2011) -
Genetically indistinguishable SNPs and their influence on inferring the location of disease-associated variants.
by: Lawrence, R, et al.
Published: (2005) -
Genotype prediction using a dense map of SNPs.
by: Evans, D, et al.
Published: (2004) -
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
by: Zabaneh, D, et al.
Published: (2011)