Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated.
The S-M checkpoint is an intracellular signaling pathway that ensures that mitosis is not initiated in cells undergoing DNA replication. We identified cid1, a novel fission yeast gene, through its ability when overexpressed to confer specific resistance to a combination of hydroxyurea, which inhibit...
Main Authors: | Wang, S, Toda, T, MacCallum, R, Harris, A, Norbury, C |
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Format: | Journal article |
Language: | English |
Published: |
2000
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