Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection.

Structural characterization of peptides restricted by major histocompatibility complex (MHC) class I molecules has identified residues critical for MHC class I binding and for T-cell receptor recognition. For example, optimal peptides fitting into the murine MHC class I Db groove are 9 to 11 amino a...

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Bibliographic Details
Main Authors: Oldstone, M, Lewicki, H, Borrow, P, Hudrisier, D, Gairin, J
Format: Journal article
Language:English
Published: 1995

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