Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.
Persisting infections are often associated with chronic T cell activation. For certain pathogens, this can lead to T cell exhaustion and survival of what is otherwise a cleared infection. In contrast, for herpesviruses, T cells never eliminate infection once it is established. Instead, effective imm...
Κύριοι συγγραφείς: | , , , , , , , , |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2012
|