Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

The Zika virus (ZIKV) epidemic has resulted in congenital abnormalities in fetuses and neonates. Although some cross-reactive dengue virus (DENV)-specific antibodies can enhance ZIKV infection in mice, those recognizing the DENV E-dimer epitope (EDE) can neutralize ZIKV infection in cell culture. We...

书目详细资料
Main Authors:	Fernandez, E, Dejnirattisai, W, Cao, B, Scheaffer, SM, Supasa, P, Wongwiwat, W, Esakky, P, Drury, A, Mongkolsapaya, J, Moley, KH, Mysorekar, IU, Screaton, GR, Diamond, MS
格式:	Journal article
语言:	English
出版:	Springer Nature 2017

相似书籍

Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope
由: Alexander Rouvinski, et al.
出版: (2017-05-01)

A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection
由: Campos, JL, et al.
出版: (2019)

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses
由: Sharma, A, et al.
出版: (2021)

Evolution of neurovirulent Zika virus
由: Screaton, G, et al.
出版: (2017)

The immunology of Zika virus
由: Culshaw, A, et al.
出版: (2018)

Dengue and Zika virus cross-reactive human monoclonal antibodies protect against Spondweni virus infection and pathogenesis in mice
由: Salazar, V, et al.
出版: (2019)

Longitudinal analysis of antibody cross-neutralization following Zika and dengue virus infection in Asia and the Americas
由: Montoya, M, et al.
出版: (2018)

The immunology of Zika Virus [version 1; referees: 2 approved]
由: Abigail Culshaw, et al.
出版: (2018-02-01)

Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus
由: Renner, M, et al.
出版: (2018)

Interferon lambda protects the female reproductive tract against Zika virus infection
由: Elizabeth A. Caine, et al.
出版: (2019-01-01)

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy
由: Alex W. Wessel, et al.
出版: (2020-10-01)

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice
由: Vanessa Salazar, et al.
出版: (2019-02-01)

Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus
由: J. A. Swanstrom, et al.
出版: (2016-09-01)

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys
由: Abbink, P, et al.
出版: (2018)

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.
由: Dejnirattisai, W, et al.
出版: (2014)

Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes
由: Rajeshwer S. Sankhala, et al.
出版: (2023-08-01)

Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection
由: Maximilian Koblischke, et al.
出版: (2018-05-01)

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus
由: Dejnirattisai, W, et al.
出版: (2014)

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers
由: Stefan W. Metz, et al.
出版: (2017-07-01)

B-cell epitope discovery: The first protein flexibility-based algorithm–Zika virus conserved epitope demonstration
由: Daniel W. Biner, et al.
出版: (2023-01-01)

B-cell epitope discovery: The first protein flexibility-based algorithm-Zika virus conserved epitope demonstration.
由: Daniel W Biner, et al.
出版: (2023-01-01)

Drugs to limit Zika virus infection and implication for maternal-fetal health
由: Ankur Kumar, et al.
出版: (2022-08-01)

Guillain-Barré syndrome following Zika virus infection is associated with a diverse spectrum of peripheral nerve reactive antibodies
由: Davies, AJ, et al.
出版: (2022)

Corrigendum: Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection
由: Maximilian Koblischke, et al.
出版: (2018-09-01)

In Silico BCell Epitope Design of Zika Virus Vaccine Using “Zika Virus Isolate Zika Virus/H sapiensTc/Tha/2006/CVD_06020 Complete Genome”
由: Lisa Savitri, et al.
出版: (2023-09-01)

Immunogenicity and efficacy of Zika virus envelope domain III in DNA, protein, and ChAdOx1 adenoviral-vectored vaccines
由: López-Camacho, C, et al.
出版: (2020)

Epitope-Driven Vaccine Development for Zika Virus: A Bioinformatics Approach
由: Riska Ayu Sutriyansyah, et al.
出版: (2024-12-01)

Identification of immunodominant T cell epitopes induced by natural Zika virus infection
由: Christopher S. Eickhoff, et al.
出版: (2023-08-01)

Potent neutralizing human monoclonal antibodies preferentially target mature dengue virus particles: implication for novel strategy of dengue vaccine
由: Tsai, W, et al.
出版: (2018)

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients
由: Amrun, SN, et al.
出版: (2019)

Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics
由: Rohan Raj Roy, et al.
出版: (2025-02-01)

In silico prediction of a highly immunogenic and conserved epitope against Zika Virus
由: Debasish Paul, et al.
出版: (2021-01-01)

Novel differential linear B‐cell epitopes to identify Zika and dengue virus infections in patients
由: Siti Naqiah Amrun, et al.
出版: (2019)

Structural analysis of a dengue cross-reactive antibody complexed with envelope domain III reveals the molecular basis of cross-reactivity.
由: Midgley, C, et al.
出版: (2012)

Molecular mimicry between Zika virus and central nervous system inflammatory demyelinating disorders: the role of NS5 Zika virus epitope and PLP autoantigens
由: Laise Carolina França, et al.
出版: (2023-04-01)

Pregnancy and Zika virus
由: T. V. Startseva, et al.
出版: (2020-07-01)

Designing Multi‐Epitope Subunit Vaccine Candidate for Zika Virus Utilizing In silico Tools
由: Fatemeh Shams Moattar, et al.
出版: (2022-03-01)

Develop dengue and zika virus inhibitors : simulation of small drug molecules with e-protein dimer
由: Chai, Juan Zhe
出版: (2018)

Zika Virus
由: Sophie Masmejan, et al.
出版: (2020-10-01)

Zika Vírus
由: Cynthia Molina Bastos, et al.
出版: (2016-10-01)