Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

The Zika virus (ZIKV) epidemic has resulted in congenital abnormalities in fetuses and neonates. Although some cross-reactive dengue virus (DENV)-specific antibodies can enhance ZIKV infection in mice, those recognizing the DENV E-dimer epitope (EDE) can neutralize ZIKV infection in cell culture. We...

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Huvudupphovsmän: Fernandez, E, Dejnirattisai, W, Cao, B, Scheaffer, SM, Supasa, P, Wongwiwat, W, Esakky, P, Drury, A, Mongkolsapaya, J, Moley, KH, Mysorekar, IU, Screaton, GR, Diamond, MS
Materialtyp: Journal article
Språk:English
Publicerad: Springer Nature 2017

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