Membrane thickness and the mechanism of action of the short peptaibol trichogin GA IV.
Trichogin GA IV (GAIV) is an antimicrobial peptide of the peptaibol family, like the extensively studied alamethicin (Alm). GAIV acts by perturbing membrane permeability. Previous data have shown that pore formation is related to GAIV aggregation and insertion in the hydrophobic core of the membrane...
Main Authors: | Bobone, S, Gerelli, Y, De Zotti, M, Bocchinfuso, G, Farrotti, A, Orioni, B, Sebastiani, F, Latter, E, Penfold, J, Senesi, R, Formaggio, F, Palleschi, A, Toniolo, C, Fragneto, G, Stella, L |
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Format: | Journal article |
Language: | English |
Published: |
2013
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