Formation of TCR dimers/trimers as a crucial step for T cell activation.
T cell activation involves specific interactions between the TCR and peptides presented by the MHC. This engagement leads to phosphorylation and subsequent internalization of the TCR complex. By analyzing the kinetics of the internalization of TCR, we found that the rate of TCR down-regulation was p...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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