3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues
Although biological membranes may look like a 2D assembly, they often have complex structures in their 3rd dimension. Using layer-by-layer assembly, 3D-printing can offer an advanced and unique approach for the fabrication of such models. However, printing of some widely used hydrogels, such as gela...
| Main Authors: | , , , |
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| Format: | Journal article |
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Elsevier
2018
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| _version_ | 1797083612725641216 |
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| author | Tayebi, L Rasoulianboroujeni, M Cui, Z Ye, H |
| author_facet | Tayebi, L Rasoulianboroujeni, M Cui, Z Ye, H |
| author_sort | Tayebi, L |
| collection | OXFORD |
| description | Although biological membranes may look like a 2D assembly, they often have complex structures in their 3rd dimension. Using layer-by-layer assembly, 3D-printing can offer an advanced and unique approach for the fabrication of such models. However, printing of some widely used hydrogels, such as gelatin, encounters experimental difficulties due to their rheological properties. In this paper, we (a) discuss the complexities involved in printing gelatin, (b) offer a reproducible approach to overcome such difficulties, and (c) present the detailed design criteria and the production process of such 3D-printed gelatin membranes by exemplifying scaffolds suitable for growth of full-thickness oral mucosa as a heterogeneous tissue. |
| first_indexed | 2024-03-07T01:43:53Z |
| format | Journal article |
| id | oxford-uuid:97c12e7e-f248-4afb-b03b-cfb8ff241b37 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T01:43:53Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:97c12e7e-f248-4afb-b03b-cfb8ff241b372022-03-27T00:02:13Z3D-printed thick structured gelatin membrane for engineering of heterogeneous tissuesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:97c12e7e-f248-4afb-b03b-cfb8ff241b37Symplectic Elements at OxfordElsevier2018Tayebi, LRasoulianboroujeni, MCui, ZYe, HAlthough biological membranes may look like a 2D assembly, they often have complex structures in their 3rd dimension. Using layer-by-layer assembly, 3D-printing can offer an advanced and unique approach for the fabrication of such models. However, printing of some widely used hydrogels, such as gelatin, encounters experimental difficulties due to their rheological properties. In this paper, we (a) discuss the complexities involved in printing gelatin, (b) offer a reproducible approach to overcome such difficulties, and (c) present the detailed design criteria and the production process of such 3D-printed gelatin membranes by exemplifying scaffolds suitable for growth of full-thickness oral mucosa as a heterogeneous tissue. |
| spellingShingle | Tayebi, L Rasoulianboroujeni, M Cui, Z Ye, H 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title | 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title_full | 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title_fullStr | 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title_full_unstemmed | 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title_short | 3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| title_sort | 3d printed thick structured gelatin membrane for engineering of heterogeneous tissues |
| work_keys_str_mv | AT tayebil 3dprintedthickstructuredgelatinmembraneforengineeringofheterogeneoustissues AT rasoulianboroujenim 3dprintedthickstructuredgelatinmembraneforengineeringofheterogeneoustissues AT cuiz 3dprintedthickstructuredgelatinmembraneforengineeringofheterogeneoustissues AT yeh 3dprintedthickstructuredgelatinmembraneforengineeringofheterogeneoustissues |