Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM
Management of Crohn’s disease (CD) is moving towards the therapeutic goal of mucosal healing and using biomarkers of inflammation, faecal calprotectin (FC) and C-reactive protein (CRP), to monitor patient progress. CALM demonstrated superior mucosal healing in patients whose treatment was escalated...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Conference item |
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Oxford University Press
2018
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| _version_ | 1826286454940106752 |
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| author | Reinisch, W Panaccione, R Bossuyt, P Baert, F Armuzzi, A Travis, S Danese, S Sandborn, W D'Haens, G Berg, S Maa, J Petersson, J Neimark, E Robinson, A Colombel, J |
| author_facet | Reinisch, W Panaccione, R Bossuyt, P Baert, F Armuzzi, A Travis, S Danese, S Sandborn, W D'Haens, G Berg, S Maa, J Petersson, J Neimark, E Robinson, A Colombel, J |
| author_sort | Reinisch, W |
| collection | OXFORD |
| description | Management of Crohn’s disease (CD) is moving towards the therapeutic goal of mucosal healing and using biomarkers of inflammation, faecal calprotectin (FC) and C-reactive protein (CRP), to monitor patient progress. CALM demonstrated superior mucosal healing in patients whose treatment was escalated based on both symptoms and biomarkers than in patients managed by symptoms alone,1 but the optimal biomarker cut-offs to predict mucosal healing have not been established yet. In this analysis, association of endoscopic outcomes with FC and CRP at cut-offs from CALM was investigated. |
| first_indexed | 2024-03-07T01:44:01Z |
| format | Conference item |
| id | oxford-uuid:97ca67e8-1ef4-4fbf-851c-9e3729ae0115 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T01:44:01Z |
| publishDate | 2018 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | oxford-uuid:97ca67e8-1ef4-4fbf-851c-9e3729ae01152022-03-27T00:02:31ZBiomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALMConference itemhttp://purl.org/coar/resource_type/c_5794uuid:97ca67e8-1ef4-4fbf-851c-9e3729ae0115Symplectic Elements at OxfordOxford University Press2018Reinisch, WPanaccione, RBossuyt, PBaert, FArmuzzi, ATravis, SDanese, SSandborn, WD'Haens, GBerg, SMaa, JPetersson, JNeimark, ERobinson, AColombel, JManagement of Crohn’s disease (CD) is moving towards the therapeutic goal of mucosal healing and using biomarkers of inflammation, faecal calprotectin (FC) and C-reactive protein (CRP), to monitor patient progress. CALM demonstrated superior mucosal healing in patients whose treatment was escalated based on both symptoms and biomarkers than in patients managed by symptoms alone,1 but the optimal biomarker cut-offs to predict mucosal healing have not been established yet. In this analysis, association of endoscopic outcomes with FC and CRP at cut-offs from CALM was investigated. |
| spellingShingle | Reinisch, W Panaccione, R Bossuyt, P Baert, F Armuzzi, A Travis, S Danese, S Sandborn, W D'Haens, G Berg, S Maa, J Petersson, J Neimark, E Robinson, A Colombel, J Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title | Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title_full | Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title_fullStr | Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title_full_unstemmed | Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title_short | Biomarker correlation with endoscopic outcomes in patients with Crohn's disease: data from CALM |
| title_sort | biomarker correlation with endoscopic outcomes in patients with crohn s disease data from calm |
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