Characterisation of KEAP1 as a novel factor in DNA base damage repair and investigation of its relationship with PARPs

<p>Genomes are constantly subjected to various genotoxic stresses that can cause DNA damage, which, if unrepaired, can lead to cancer or cell death. To counteract this threat, cells have evolved a network of pathways that resolve DNA damage, termed DNA damage response (DDR). These crucial path...

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Bibliographic Details
Main Author: Rokicka, JJ
Other Authors: Lakin, N
Format: Thesis
Language:English
Published: 2023
Subjects: