An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates

Background. Hedgehog signalling, interpreted in receiving cells by Gli transcription factors, plays a central role in the development of vertebrate and Drosphila embryos. Many aspects of the signalling pathway are conserved between these lineages, however vertebrates have diverged in at least one ke...

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Bibliographic Details
Main Authors: Shimeld, S, van den Heuvel, M, Dawber, R, Briscoe, J
Format: Journal article
Language:English
Published: Public Library of Science 2007
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