An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates
Background. Hedgehog signalling, interpreted in receiving cells by Gli transcription factors, plays a central role in the development of vertebrate and Drosphila embryos. Many aspects of the signalling pathway are conserved between these lineages, however vertebrates have diverged in at least one ke...
Main Authors: | Shimeld, S, van den Heuvel, M, Dawber, R, Briscoe, J |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2007
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Subjects: |
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