Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans.

Cyclin-dependent kinases (CDKs) play crucial roles in promoting DNA replication and preventing rereplication in eukaryotic cells [1-4]. In budding yeast, CDKs promote DNA replication by phosphorylating two proteins, Sld2 and Sld3, which generates binding sites for pairs of BRCT repeats (breast cance...

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Bibliographic Details
Main Authors: Boos, D, Sanchez-Pulido, L, Rappas, M, Pearl, L, Oliver, A, Ponting, C, Diffley, J
Format: Journal article
Language:English
Published: 2011

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