Recent advances in osteoclast biology and pathological bone resorption.
The osteoclast is a bone-degrading polykaryon. Recent studies have clarified the differentiation of this cell and the biochemical mechanisms it uses to resorb bone. The osteoclast derives from a monocyte/macrophage precursor. Osteoclast formation requires permissive concentrations of M-CSF and is dr...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|