Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved influenza a antigens

Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved influenza a antigens

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Adenoviruses are potent vectors for inducing and boosting cellular immunity to encoded recombinant antigens. However, the widespread seroprevalence of neutralizing antibodies to common human adenovirus serotypes limits their use. Simian adenoviruses do not suffer from the same drawbacks. We have con...

书目详细资料
Main Authors:	Antrobus, R, Coughlan, L, Berthoud, T, Dicks, MD, Hill, A, Lambe, T, Gilbert, S
格式:	Journal article
语言:	English
出版:	Nature Publishing Group 2014

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