Constitutive dimerization of the G-protein coupled receptor, neurotensin receptor 1, reconstituted into phospholipid bilayers.

Neurotensin receptor 1 (NTS1), a Family A G-protein coupled receptor (GPCR), was expressed in Escherichia coli as a fusion with the fluorescent proteins eCFP or eYFP. A fluorophore-tagged receptor was used to study the multimerization of NTS1 in detergent solution and in brain polar lipid bilayers,...

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Príomhchruthaitheoirí: Harding, P, Attrill, H, Boehringer, J, Ross, S, Wadhams, G, Smith, E, Armitage, J, Watts, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2009